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Expemental Study On The Effect Of X-Irradiation In The Rat Bone Matrix

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Abstract

îÊíº´Â ìõãã 8ìíÀÌ µÇ´Â ÛÜà©¿¡´Ù XàÊÀ» ðÎÞÒÇÏ°í À̷κÎÅÍ õóßæµÈ ý­ 4ñÎ Ò¬ò¸ 5ñεÈ
ÛÜà©ÀÇ ù»äÉÍé Û¡ëÀßÓÀ» ËþßãÇÑ ¹Ù¿¡¼­ ´ÙÀ½°ú °°Àº Ì¿Íý¸¦ ¾òÀ» ¼ö ÀÖ¾ú´Ù.
1. 100¡­200 rads ðÎÞÒÇÑ ÛÜà©¿¡¼­´Â ÝÕЮöÎÇÑ ÍéÕÚÀÌ Îºó̵dzª Ï°ðãîÜé©áÈÀÇ Ü¨ûùá¶Ì¸Àº
κóÌÇϱ⠾î·Á¿üÀ¸³ª ê×õêµÈ ú·À» °¡Áø àéë«ä´á¬øà ¹× Íéä´á¬øฦ º¼ ¼ö ÀÖ¾ú´Ù.
2. ìéÚõîÜÀ¸·Î X àÊ ðÎÞÒåÖÀÌ ñòÊ¥ÇÔ¿¡ µû¶ó ÷òÍéá¬øàÀÇ â¦îÜÀÎ ñòÊ¥úÞßÚÀÌ Îºó̵ǰí ÀÖ
¾ú´Ù.
3. 300 rads ðÎÞÒµÈ ÛÜà©¿¡¼­´Â ͳêóöÍðËÍéÀ» ÀÌ·ç´Â ÍéÕÚÀÌ ÝÕЮöÎÇÏ°í ÍéâÐË·Àº ìéÚõîÜ
À¸·Î ³Ð¾îÁö´Â ÌËú¾ÀÌ ÀÖ¾ú´Ù.

The author studied on the side effects of x-ray irradiation to the developing mandible
of the gestation and period of grow the stage rats,
For experimental observation, 100 rads, 200 rads, and 300 rads of x-ray were
irradiated in regular order at the lower abdomen of the 8th day gestated rats.
5 weeks after conception, their offspring were sacrificed and their mandibles were
extracted with intact form.
All the extracted mandible were examined for their developing modes histological
findings.
The results were as followed
1) In 100-200 rads irradiated rats offsprings, their mandibles were not revealed any
morphological changes except of the irregular pattern of trabeculatum.
In accompany with this findings, most of all the fibroblasts and osteoclasts had their
nucleus with shrunken and eccetric position,
2) In according to the increasing x-ray irradiation, marked advent of osteoclast and
cortical bone resorption were observed.
3) In 300 rads irradiated rats offsprings, there irregular pattern of trabeculae and
windening of bone morrow cavity in their alveolar proper.

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